This is a worrisome dosage, especially when compared to other fat-burning supplements that are on the market today. So although this study suggests that raspberry ketones may help to reduce liver inflammation, more studies need to be done on humans using the appropriate dosage.
A study found that raspberry ketones may have a therapeutic role in controlling hyperlipidemia and insulin resistance among obese rats. Again, this is an animal study and the ketone doses were — milligrams per kilogram of body weight, which would be a very high dose for humans. The study does suggest, however, that raspberry ketones contribute to the upregulation of AQP7 expression, which is protein that plays a role in metabolic function.
Like most of the potential raspberry ketone benefits, more research is needed on this to indicate whether or not ketones are effective for normalizing cholesterol levels and insulin resistance in humans. A study on mice found that when 0. When researchers tested whether or not raspberry ketones work as a natural treatment for thinning hair on humans, they also found positive results.
When raspberry ketone was applied topically to the scalp, it promoted hair growth in 50 percent of humans with alopecia at five months after applications. The same researchers in Japan that reported the efficacy of raspberry ketones for hair growth evaluated its ability to improve skin elasticity in humans. They found that when 0. This was only tested on five women, but it is a bit of promising evidence offered on raspberry ketones involving humans. Traditionally, ketones found in red raspberries were used to prevent high cholesterol, diabetes and even liver cancer.
Raspberries were consumed for their ketones before supplements with much higher doses were available. Raspberries were also eaten for their nutritional value. Raspberry nutrition is quite impressive, boasting powerful antioxidants and nutrients like vitamin C , manganese, vitamin K and magnesium.
Consuming raspberries is known to help reduce inflammation, boost heart health, ease arthritic pain and fight aging. Raspberry ketones supplements are available in capsule form, and they are widely available online and in vitamin stores. Raspberry ketone supplement dosage ranges from —1, milligrams, once or twice daily. Naturally, you only eat about 0. Before you choose to use high doses of raspberry ketone supplements, it would be best to have medical research involving humans that supports the biological effects first.
There is no scientific research that evaluates the side effects of these doses on humans or the impact that they have on human cells and organs. You can get ketones in your diet by eating berries including raspberries, blackberries and cranberries and fruits like kiwi, apples, grapes and peaches. However, she cautions, it might not be safe for people with certain health conditions. This may also have an effect on people who have COPD or asthma conditions and may make their conditions worse.
For more fitness, diet, and weight loss news, follow weightloss on Twitter from the editors of EverydayHealth. By subscribing you agree to the Terms of Use and Privacy Policy. Health Topics. Our evidence-based analysis on raspberry ketone features 20 unique references to scientific papers. Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists.
We have a strict editorial process. This page features 20 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of references for this page. Raspberry ketone is the compound responsible for many flavoring and aromatic qualities of cosmetics and processed foods. When present in high doses, raspberry ketone can exert fat burning effects on various areas of the fat cell.
These effects may be similar to those of ephedrine and synephrine. It should be noted that all evidence for the effects of raspberry ketone has only been observed in vitro in a test tube. Though researchers are able to raise the concentrations of ketones in a single cell during studies, these same concentrations cannot be replicated in the human body, particularly through oral supplementation. There is no human evidence for the effects of raspberry ketones. Studies on rats have used a dosage range of.
This dose is very high compared to other fat burning compounds, so for that reason the standard supplemental dose of raspberry ketones for humans is in the mg range.
There is no solid evidence for the effectiveness of the doses listed below. Rat dosages correlate to the following human doses:. There is no human evidence for the effectiveness of raspberry ketones. Raspberry ketones cannot be concentrated in the human body the same way they are concentrated during studies done outside the body, on single cells. However, raspberry ketones did not directly lead to weight loss by causing the body to burn more fat. It is important to note that raspberry ketones have nothing to do with ketosis or the ketogenic diet.
In a state of ketosis, the body burns fat for energy rather than glucose. Ketosis is a process that happens in the body. Taking raspberry ketones will not trigger ketosis or support a keto diet. Learn more about ketosis here. Diets that are very high in fat can cause a condition called nonalcoholic fatty liver disease. The findings of a animal study suggest that raspberry ketones may reduce the risk of this disease in rats who eat a high fat diet.
However, as with other research on animals, it is not necessarily the case that the results are applicable to humans. Eating raspberries may reduce chronic inflammation , which experts believe to play a role in the development of numerous health conditions.
One study found that red raspberries reduced swelling and other symptoms of arthritis in rats with this condition, but there is a need for more studies to investigate this effect.
Scientists are yet to research the link between inflammation and raspberry ketones in humans. Dementia is a complex brain disease that doctors still do not fully understand. Some evidence suggests that inflammation may play a role. As raspberry ketones may reduce inflammation, they might also lower the risk of dementia.
No studies have directly assessed the role of raspberries or raspberry ketones in humans who have dementia or have a higher risk of developing it. Some research has looked at how ellagic acid, a phytochemical in raspberries, affects the formation of amyloid plaques.
The study showed that ellagic acid might slow the development of plaques. If this is the case, eating whole raspberries may be more beneficial than taking raspberry ketones as a supplement. However, more research is necessary to confirm this potential benefit. As there have not been well-designed clinical trials involving humans, doctors and researchers do not know whether raspberry ketones are safe.
Scientists are also unclear whether certain groups may be at greater risk of raspberry ketone side effects than others. In one case , a woman using raspberry ketones experienced organ failure.
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